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Department of Psychiatry
Nagoya City University
Medical School
Mizuho-cho, Mizuho-ku, Nagoya
467-8601 JAPAN
Phone: +81-52-853-8271
FAx: +81-52-852-0837
Research from our Lithium Clinic and affiliated groups:

Ono, Y., Kawakami, N., Nakane, Y., Nakamura, Y., Tachimori, H., Iwata, N., Uda, H., Nakane, H., Watanabe, M., Naganuma, Y., Furukawa, T. A., Hata, Y., Kobayashi, M., Miyake, Y., Tajima, M., Takeshima, T. & Kikkawa, T. (in press) Prevalence and risk factors for suicide-related outcomes in the World Health Organization World Mental Health Surveys Japan. Psychiatry and Clinical Neurosciences.

Cipriani, A., Furukawa, T. A., Geddes, J., Malvini, L., Signoretti, A., Churchill, R., McGuire, H., Nakagawa, A. & Barbui, C. (in press) Does randomised evidence support a first-line antidepressant for adults with acute major depression? A systematic review and meta-analysis. Journal of Clinical Psychiatry.

Watanabe, N., Omori, I. M., Nakagawa, A., Cipriani, A., Barbui, C., McGuire, H., Churchill, R. & Furukawa, T. A. (in press) Mirtazapine versus other antidepressants in the acute-phase treatment of adults with major depression: Systematic review and meta-analysis. Journal of Clinical Psychiatry.

Nakagawa, A., Watanabe, N., Omori, I. M., Furukawa, T. A., Barbui, C., Cipriani, A., McGuire, H. & Churchill, R. (in press) Efficacy and acceptability of milnacipran in the treatment of major depression in comparison with other antidepressants: a systematic review and meta-analysis. CNS Drugs.

Omori, I., Watanabe, N., Nakagawa, A., Akechi, T., Cipriani, A., Barbui, C., McGuire, H., Churchill, R. & Furukawa, T. A. (in press) Efficacy, tolerability and side effect profie of fluvoxamine for major depression: meta-analysis. Journal of Psychopharmacology.

Azuma, H., Fujita, A., Sato, K., Arahata, K., Otsuki, K., Hori, M., Mochida, Y., Uchida, M., Yamada, T., Akechi, T. & Furukawa, T. A. (in press) Postictal cardiovascular response predicts therapeutic efficacy of electroconvulsive therapy for depression. Psychiatry and Clinical Neurosciences.

Sartorius, N., Baghai, T. C., Baldwin, D. S., Barrett, B., Brand, U., Fleischhacker, W., Goodwin, G., Grunze, H., Knapp, M., Leonard, B. E., Lieberman, J., Nakane, Y., Pinder, R. M., Schatzberg, A. F., Svestka, J., Baumann, P., Ghalib, K., Markowitz, J. C., Padberg, F., Fink, M., Furukawa, T., Fountoulakis, K. N., Jensen, P., Kanba, S. & Riecher-Rossler, A. (2007) Antidepressant medications and other treatments of depressive disorders: a CINP Task Force report based on a review of evidence. International Journal of Neuropsychopharmacology, 10 Suppl 1, S1-207.

Fujita, A., Azuma, H., Kitamura, T., Takahasi, K., Akechi, T. & Furukawa, T. A. (2008) Adequacy of continuation and maintenance treatments for major depression in Japan. Journal of Psychopharmacology, 22, 153-156.

Barbui, C., Furukawa, T. A. & Cipriani, A. (2008) Effectiveness of paroxetine in the acute phase treatment of adults with major depression: a systematic re-examination of published and unpublished randomised data. Canadian Medical Association Journal, 178, 296-305.

Furukawa, T. A., Fujita, A., Harai, H., Yoshimura, R., Kitamura, T. & Takahashi, K. (2008) Definitions of recovery and outcomes of major depression: results from a 10-year follow-up. Acta Psychiatrica Scandinavica, 117, 35-40.

Kojima, M., Hayano, J., Tokudome, S., Suzuki, S., Ibuki, K., Tomizawa, H., Nakata, A., Seno, H., Toriyama, T., Kawahara, H. & Furukawa, T. A. (2007) Independent associations of alexithymia and social support with depression in hemodialysis patients. Journal of Psychosomatic Research, 63, 349-356.

Furukawa, T. A., Cipriani, A., Barbui, C. & Geddes, J. R. (2007) Long-term treatment of depression with antidepressants: A systematic narrative review. Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie, 52, 545-552.

Geddes, J. R., Furukawa, T. A., Cipriani, A. & Barbui, C. (2007) Depressive disorder needs an evidence base commensurate with its public health importance. Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie, 52, 543-544.

Cipriani, A., Geddes, J. R., Furukawa, T. A. & Barbui, C. (2007) Metareview on short-term effectiveness and safety of antidepressants for depression: an evidence-based approach to inform clinical practice. Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie, 52, 553-562.

Furukawa, T. A., Akechi, T., Azuma, H., Okuyama, T. & Higuchi, T. (2007) Evidence-based guidelines for interpretation of the Hamilton Rating Scale for Depression. Journal of Clinical Psychopharmacology, 27, 531-534.

Tabuse, H., Kalali, A., Azuma, H., Ozaki, N., Iwata, N., Naitoh, H., Higuchi, T., Kanba, S., Shioe, K., Akechi, T. & Furukawa, T. A. (2007) The new GRID Hamilton Rating Scale for Depression demonstrates excellent inter-rater reliability for inexperienced and experienced raters before and after training. Psychiatry Research.

Watanabe, N., Hunot, V., Omori, I. M., Churchill, R. & Furukawa, T. A. (2007) Psychotherapy for depression among children and adolescents: a systematic review. Acta Psychiatrica Scandinavica, 116, 84-95.

Cipriani, A., Malvini, L., Furukawa, T. A. & Barbui, C. (2007) Relationship Between Quality of Reports of Antidepressant Randomized Controlled Trials and Treatment Estimates: Systematic Review, Meta-Analysis, and Meta-Regression Analysis. Journal of Clinical Psychopharmacology, 27, 352-356.

Azuma, H., Fujita, A., Sato, K., Arahata, K., Otsuki, K., Hori, M., Mochida, Y., Uchida, M., Yamada, T., Akechi, T. & Furukawa, T. A. (2007) Postictal suppression correlates with therapeutic efficacy for depression in bilateral sine and pulse wave electroconvulsive therapy. Psychiatry and Clinical Neurosciences, 61, 168-173.

Segawa, K., Azuma, H., Sato, K., Yasuda, T., Arahata, K., Otsuki, K., Tohyama, J., Soma, T., Iidaka, T., Nakaaki, S. & Furukawa, T. A. (2006) Regional cerebral blood flow changes in depression after electroconvulsive therapy. Psychiatry Research Neuroimaging, 147, 135-143.

Cipriani, A., Barbui, C., Brambilla, P., Furukawa, T., Hotopf, M. & Geddes, J. (2006) Are all antidepressants really the same? The case of fluoxetine: a systematic review. Journal of Clinical Psychiatry, 67, 850-864.

Akechi, T., Iwasaki, M., Uchitomi, Y., Tsugane, S. (2006). Alcohol consumption and suicide among middle-aged men in Japan. British Journal of Psychiatry, 188, 231-236

Kitamura, T., Yoshida, K., Okano, T., Kinoshita, K., Hayashi, M., Toyoda, N., Ito, M., Kudo, N., Tada, K., Kanazawa, K., Sakumoto, K., Satoh, S., Furukawa, T. & Nakano, H. (2006) Multicentre prospective study of perinatal depression in Japan: incidence and correlates of antenatal and postnatal depression. Archives of Women's Mental Health, 9, 121-130.

Okumura, K. & Furukawa, T. A. (2006) Remission rates of milnacipran 100 mg/day and 150 mg/day in the long-term treatment of major depression. Clinical Drug Investigation, 26, 135-142.

Fujita, A., Nakaaki, S., Segawa, K., Azuma, H., Sato, K., Arahata, K., Otsuki, K., Hori, M., Mochida, Y., Uchida, M., Yamada, T., Nakamura, C., Akechi, T. & Furukawa, T. A. (2006) Memory, attention and executive function before and after sine- and pulse-wave electroconvulsive therapy for treatment-resistant major depression. Journal of ECT, 22, 107-112.

Kobayakawa, M., Yamawaki, S., Hamazaki, K., Akechi, T., Inagaki, M., Uchitomi, T. (2005). Levels of omega-3 fatty acid in serum phospholipids and depression in patients with lung cancer. British Journal of Cancer, 93, 1329-1333.

Cipriani, A., Brambilla, P., Furukawa, T., Geddes, J., Gregis, M., Hotopf, M., Malvini, L. & Barbui, C. (2005) Fluoxetine versus other types of pharmacotherapy for depression. Cochrane Database Syst Rev, 4, CD004185.

Furukawa, T. A., Streiner, D. L., Azuma, H., Higuchi, T., Kamijima, K., Kanba, S., Ozaki, N., Aoba, A., Murasaki, M. & Miura, S. (2005) Cross-cultural equivalence in depression assessment: Japan-Europe-North American study. Acta Psychiatrica Scandinavica, 112, 279-285.

Hiroe, T., Kojima, M., Yamamoto, I., Nojima, S., Kinoshita, Y., Hashimoto, N., Watanabe, N., Maeda, T. & Furukawa, T. A. (2005) Gradations of clinical severity and sensitivity to change assessed with the Beck Depression Inventory-II in Japanese patients with depression. Psychiatry Research, 135, 229-235.

Ichimura A, Matsumoto H, Kimura T, Okuyama T, Watanabe T, Nakagawa Y, Yamamoto I, Inokuchi S, Hosaka T. (2005) Changes in mental disorder distribution among suicide attempters in mid-west area of Kanagawa. Psychiatry and Clinical Neurosciences 59(2):113-8.

Furukawa, T. A. (2004). No more secrets. Rapid response to Lenzer J (2004) Secret US report surfaces on antidepressants in children. BMJ 329: 307. bmj.com 10 August. (To read this, click here.)

Segawa, K., Kanai, T., Takeuchi, H., Sato, K., Azuma, H., Matsui, T., Nakaaki, S. & Furukawa, T. (2004). Regional cerebral blood flow before and after ECT: comparison between responders and non-responders. Journal of Affective Disorders 78 Supplement 1, S110.

Yamada, K., Nagayama, H., Tsuchiyama, K., Kitamura, T. & Furukawa, T. (2003). Coping behavior in depressed patients: a longitudinal study. Psychiatry Research 121, 169-177

Kanai, T., Takeuchi, T., Furukawa, T. A., Yoshimura, R., Imaizumi, T., Kitamura, T. & Takahashi, K. (2003). Time to recurrence after recovery from major depressive episodes and its predictors. Psychological Medicine 33, 838-845.
[This paper is featured in an accompanying editorial by Alan Lee, author of an earlier seminal follow-up study of depressive disorders: Lee, A. (2003) Better outcomes for depressive disorders? [editorial] Psychological Medicine 33, 769-774.]
[This paper was further summarized and commented on by WE Craighead et al in Evidence-Based Mental Health 7, 5]

Takeuchi, H., Hiroe, T., Kanai, T., Morinobu, S., Kitamura, T., Takahashi, K. & Furukawa, T. A. (2003). Childhood parental separation experiences and depressive symptomatology in acute major depression. Psychiatry and Clinical Neurosciences 57, 215-219.

 

 

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Research projects in progress:

1) Group for Longitudinal Affective Disorders Study (GLADS) is a national multi-center naturalistic follow-up study of broadly-defined mood disorders. It is currently in its 7-10th year of follow-up.

2) Electrophysiological and imaging studies of modified ECT



  ©1999-2007 Dept of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences